Bioorthogonal chemistry（生物正交化学）

Bioorthogonal chemistry（生物正交化学） DBCO , BCN , PEG modified propyne and azide, S-tetrazine series, TCO and cyclopropene and other excellent bio-orthogonal reaction reagents.

测试

Dibenzocyclooctyne （DBCO）

DBCO (Dibenzocyclooctyne) is used in the azido-acetylene cycloaddition (SPAAC) reaction without the catalysis of copper ions. The second-order kinetic constant of this reaction can reach 1.The DBCO family of products includes DBCO-ACID, DBCO-amine, DBCO-PEG-COOH, DBCO-PEG-amine which can be used for further linkage, as well as DBCO-labeled Biotin, fluorescent dyes and biochemical small molecules.

Bicyclo[6,1,0]decyne （BCN）

Cyclopropane cyclooctylyne (BCN, bicyclic [6.1.0] nonyne) can react with azido-labeled molecules or biomolecules to form stable triazole linkages through catalyst-free click chemistry. endo-BCN-OH, endo-BCN-PNB, endo-BCN-PEG-acid and so on.

2-Cyclooctyne-acetic acid （2-环辛炔-乙酸）

1,2,4,5-tetrazine（1,2,4,5-四嗪）

1,2,4,5 - four oxazine with large tensile ring olefins, such as the small size of the ring propylene and trans cyclooctene (TCO) for biological orthogonal with the fastest reaction rate without catalyst, has been successfully applied to the antibody tag and a variety of applications such as protein modification.

Trans-Cyclooctene （TCO）

Trans Cyclooctene (TCO) as pro dienes and S - four oxazine (Tetrazine) under physiological conditions of reaction has the advantages of without catalyst, the reaction rate is fast, has been widely used in biology and materials science research.

Cyclopropene（环丙烯）

Cyclopropene, as an amphiphilic diene, has a fast reaction rate with s-tetrazine. Because of the smaller size of cyclopropene compared with TCO, it is very suitable for labeling biochemical small molecules without affecting their original functions.

Cleavage Probes（可裂解探针）

Contains SS keys, DDE, Diazo, PC and reagents capable of splitting functional groups by light or UV.

Alkyne（炔）

Compounds containing terminal alkynes can form stable 1,2,3-triazoles by copper-catalyzed click-chemical reactions with Azide anion or biomolecules.

Azide（叠氮）

Compounds containing azides can form stable 1,2,3-triazoles by the copper-catalyzed click-chemical reaction of azides-alkynes with compounds containing alkynes or biomolecules.

Bio-orthogonal Shear reaction（生物正交剪切反应）

(2E)-TCO, N-(2E)-TCO-L-lysine, as amphiphilic Diene, can react with s-tetrazine by bio-orthogonal Shear.

Click chemical copper ion ligand（点击化学铜离子配体）

Click chemical copper ion ligand contains BTTES, TBTA, BTTP, BTTAA, THPTA .

Derivatives of norbornene（降冰片烯衍生物）

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