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Compounds containing terminal alkynes can form stable 1,2,3-triazoles by copper-catalyzed click-chemical reactions with Azide anion or biomolecules.
Alkyne（炔）
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Recent high-impact factor publications (IF > 10) by customers using our company's products
- Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment
- A Versatile One-Step Enzymatic Strategy for Efficient Imaging and Mapping of Tumor-Associated Tn Antigen
- Surface-anchored tumor microenvironment-responsive protein nanogel-platelet system for cytosolic delivery of therapeutic protein in the post-surgical cancer treatment
- Genetically Incorporated Non-Canonical Amino Acids
- Boosting Dye-Sensitized Luminescence by Enhanced Short-Range Triplet Energy Transfer
- Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling
- Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling
- A proof-of-concept study on bioorthogonal-based pretargeting and signal amplify radiotheranostic strategy
- Bioengineered Platelets Combining Chemotherapy and Immunotherapy for Postsurgical Melanoma Treatment: Internal Core-Loaded Doxorubicin and External Surface-Anchored Anti-PDL1 Antibody Backpacks
- Scalable Synthesis of Highly Stable Cyclopropene Building Blocks: Application for Bioorthogonal Ligation with Tetrazines
- Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates
- Reversible control of tetrazine bioorthogonal reactivity by naphthotube-mediated host-guest recognition
- An Optimized Isotopic Photocleavable Tagging Strategy for SiteSpecific and Quantitative Profiling of Protein O‑GlcNAcylation in Colorectal Cancer Metastasis
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